• Significantly elevated levels of DNA damage observed

  2019-09-11

  

  Significantly elevated levels of DNA damage observed in peripheral blood of tea garden women workers indicate the occupational exposure. The same was observed in cholinesterase activities, which detected lower activity in the exposed group compared to non-exposed. Large volumes of pesticides are use

• Programmed cell death via apoptosis is associated with

  2019-09-11

  

  Programmed cell death via apoptosis is associated with a series of morphological and biochemical characteristics, including cell shrinkage, the rapid increase of intracellular calcium, nuclear condensation, DNA fragmentation and the formation of apoptotic bodies. Known as a shared feature of most ap

• Cy3 TSA Fluorescence System Kit pathway Our comparison of al

  2019-09-11

  

  Our comparison of all ERα (iso)forms with ERβ immunostaining suggests that overall ERβ expression is lower than that of ERα isoforms. This contrasts the so far reported data for ERs in the lung, but is not a paradox; in pathology routine, ER positivity is defined stricto senso by nuclear WT ERs. As

• Cell migration and invasion are central

  2019-09-10

  

  Cell migration and invasion are central processes in the development and metastasis of cancer. The regulation of cell migration by DDR1 has been reported in many types of cancer cell lines; however, conflicting results have been reported regarding the inhibitory as well as promotive effects of DDR1

• br Acknowledgements br This work was supported by grants fro

  2019-09-10

  

  Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (Grant No.: 30260088) and the prophase research for National “973” Project of China (Grant No.: 2007CB116203). The DNA sequences of Hbvp1 and the Hbvp1 promoter were deposited in GenBank, an

• The goal of this paper is to

  2019-09-10

  

  The goal of this Reutericyclin paper is to investigate the penalized empirical likelihood method for the Cox model, as a competitor to the penalized partial likelihood. Since empirical likelihood (EL) was proposed by Owen, 1988, Owen, 2001, empirical likelihood methods have been investigated well f

• 96 4 br Acknowledgements br Introduction In Arabidopsis thal

  2019-09-10

  

  Acknowledgements Introduction In Arabidopsis thaliana (L.) Heynh, there are at least four copies of the caseine kinase-like gene Ck1, which is involved in peptide phosphorylation in mammals [1]. These genes are distributed on 96 4 1, 2, 4, and 5. A similar number of copies for Ck1 have been i

• The absence of an observable time

  2019-09-10

  

  The absence of an observable time dependence of kobs on inhibitor concentration for 22(R)-hydroxy Cholesterol 3 with AChE and compounds 1, 3 and 4 with BuChE parallels a similar absence of time dependence for some related fluoro ketones with AChE. Nair et al. found that trifluoromethyl acetophenones

• br Acknowledgements br Introduction Water and electrolytes c

  2019-09-10

  

  Acknowledgements Introduction Water and electrolytes constitute an integral part of all living things, and trpv1 governing their movements play important roles in a wide variety of physiological and/or pathophysiological processes. Given the importance of channel proteins in cancer cell prolif

• To develop antagonists selective for the mouse EP

  2019-09-10

  

  To develop antagonists selective for the mouse EP1 receptor, we started with compound (), synthesized as previously described (). Diethyl dipicolinic 3463 () was reduced with NaBH to . Parikh–Doering oxidation of with sulfur trioxide–pyridine complex and DMSO produced the unstable aldehyde . 4-Chlor

• ApoE is secreted from astrocytes

  2019-09-10

  

  ApoE is secreted from astrocytes/glia into the interstitial fluid and is important for metabolizing Aβ because of its propensity for binding Aβ as a cholesterol and phospholipid acceptor in reverse cholesterol transport [8]. Aβ oligomers show a direct toxicity to neurons, and ApoE inhibits oligomer

• br Perspective and conclusion Collagen

  2019-09-10

  

  Perspective and conclusion Collagen Toolkits II and III have been used to determine the CW069 for DDR1 and DDR2, and the main binding site is the GVM-GFO motif [103,108]. The co-crystal structure of the DS domain of human DDR2 bound to a synthetic collagen-like peptide containing the GVM-GFO mot

• Like all other cellular processes ubiquitination is also

  2019-09-10

  

  Like all other cellular processes, ubiquitination is also tightly regulated; more so, as myriads of pathways are controlled via this conjugation and dysregulation of ubiquitination has been implicated in various diseases including cancer [16], [17]. Quite a few of such regulatory mechanisms that con

• Protein kinase casein kinase CK comprises a

  2019-09-09

  

  Protein kinase casein kinase 1 (CK1) comprises a family of highly related, constitutively active serine/threonine protein kinases (reviewed by [15]). CK1 is involved in controlling a wide variety of different cellular events including protein turnover [16], [17], nuclear import [18] and the cellular

• Next to organophosphates carbamates and metals cholinesteras

  2019-09-09

  

  Next to organophosphates, carbamates and metals, cholinesterase activity can also be affected by other pesticides, such as newer generation neonicotinoid insecticides (NN). NNs do not inhibit AChE activity via the organophosphate-sensitive binding site of the enzyme, but rather, by acting as a struc

16369 records 990/1092 page Previous Next First page 上5页 986987988989990 下5页 Last page