• The expression of DDR receptor has regulated by numerous

  2019-11-13

  

  The expression of DDR2 receptor has regulated by numerous types of factors depending upon the cell type. During the osteogenic differentiation, the transcription factorATF4 combined with CCAAT/enhancer binding site in the DDR2 promoter, which is responsible for induction of DDR2 transcription [24].

• br Results br Discussion It has been thought that commitment

  2019-11-13

  

  Results Discussion It has been thought that commitment to the plasma cell fate begins while ha peptide are still in the GC (Suan et al., 2017, Victora and Nussenzweig, 2012), but the main obstacle to test this model and, if correct, to clarify how the plasma cell-prone GC cells develop has be

• br Results and discussion In

  2019-11-13

  

  Results and discussion In the present study, we used a set of compounds (Fig. 2) consisting of ATP (a), dATP (b), an ATP analog containing β,γ-nonhydrolyzable hypophosphate P-P bond (c), and three pairs of P-diastereoisomers of α-thio-ATP analogs (d,e,f) containing a sulfur ascorbic acid instead

• isethionate br Acknowledgements Thanks are due to Science an

  2019-11-13

  

  Acknowledgements Thanks are due to Science and Technology Development Fund – Egypt for the Research Support Technology Development Grant (RSTDG) no. 12626. Our deep thanks and gratitude is also extended to National Cancer Institute (NCI), Bethesda, Maryland, USA for performing the anticancer eval

• Disuflo Cy5 azide receptor KSTDs are generally reported to b

  2019-11-13

  

  — Δ1-KSTDs are generally reported to be intracellular enzymes, either soluble or bound to subcellular particles. For instance, the enzymes from C. testosteroni ATCC 11996 and ATCC 17410 [50,90,99], R. equi [29], and N. simplex ATCC 6946 [52] were particulate-bound. On the other hand, the Δ1-KSTDs f

• Previous studies from our laboratory

  2019-11-12

  

  Previous studies from our laboratory in CD1 mice using the incisional postoperative pain model have shown that the incision induces significant mechanical postoperative hyperalgesia lasting between 7 and 10days, with peak effect between 4h-2days (Cabañero et al., 2009a, Cabañero et al., 2009b, Campi

• Notochord is a transient structure differentiating at

  2019-11-12

  

  Notochord is a transient structure differentiating at early stage during embryogenesis that is at the origin of vertebral bodies in all vertebrates. In zebrafish, it is composed of vacuolated Results surrounded by a unique ECM structure improperly called notochordal BM. As in chicken and amphibians,

• The role of ETB clearing receptors has

  2019-11-12

  

  The role of ETB clearing receptors has been studied in detail in endothelial cell–specific ETB knock-out mice. In these animals, clearance of an intravenous atp citrate lyase inhibitor of labeled ET-1 was reduced significantly compared with wild-type controls. Importantly, functioning ETB were reta

• It is known that cigarette smoke increases

  2019-11-12

  

  It is known that cigarette smoke increases the oxidative burden in the lungs of mice with emphysema, which leads to oxidative stress [[34], [35], [36]]. However, in addition to cigarette smoke, studies have shown that endogenous oxidative stress is associated with proteolytic ion channels in severa

• br Experimental section br Author contributions br Acknowled

  2019-11-12

  

  Experimental section Author contributions Acknowledgements Introduction Many alk pathway in cells are sequential enzymatic reactions where the product of one enzyme serves as the substrate of a second enzyme (1, 2). Experimental evidence suggests that some of these consecutive enzyme-ca

• br Discussion The differences in the

  2019-11-12

  

  Discussion The differences in the kinetic properties of L-AmDH and LeuDH presented herein reflect a different kinetic mechanism. When compared to its parent enzyme, L-AmDH displayed a different substrate binding order, lower affinity for the keto substrate, and stronger product inhibition. The tw

• The anxiolytic like responses produced by anti SVG

  2019-11-12

  

  The anxiolytic-like responses produced by anti-SVG-30 suggests that CRF2 receptors mediate not only the elicitation of anxiety behavior induced by prior stress, i.e. conditioned freezing, but also unconditioned anxiety behavior induced by exposure to the unfamiliar environment of the elevated plus m

• Based on the finding described above the present

  2019-11-12

  

  Based on the finding described above, the present study was designed to investigate the effects of specific CRF receptors, CRF1 and CRF2, in the BLA and CeA on the duration of TI in guinea pigs (Cavia porcellus). To this end, we evaluated whether administration of the CRF1 THZ2 receptor antagonist C

• It is well known that the tumor suppressor

  2019-11-12

  

  It is well known that the tumor suppressor p53 plays an important role in regulating the HATU and cellular senescence [43,46,48]. For example, FOXO4 could interact with P53, which selectively induced apoptosis in senescent cells [48]. In addition, loss of MECP2 was found to lead to the induction of

• Furthermore collagen could be further utilized to surface

  2019-11-11

  

  Furthermore, collagen could be further utilized to surface modification of biologically inert materials, such as polymer materials and metal materials, which are always hydrophobic, lacking functional groups and poor cell adhesion. Therefore, various strategies have been tested to improve the proper

16276 records 946/1086 page Previous Next First page 上5页 946947948949950 下5页 Last page