• The Penicillium strain used in this work was isolated from

  2021-04-15

  

  The Penicillium strain used in this work was isolated from Atlantic forest soil and previously screened as lipase producer (Tauk-Tornisielo et al., 2005). The immobilization was previously evaluated using hydrophobic supports, i.e. agarose based butyl-(But), phenyl-(Phe) and octyl-Sepharose (Oct), a

• Recently cross talk between DDR and

  2021-04-15

  

  Recently, cross-talk between DDR2 and the insulin receptor and between Notch1 and DDR1 was proposed. Stimulation of cells with collagen I and insulin promotes Tyr740 as well as total tyrosine phosphorylation of DDR2 receptor to a greater extent than the phosphorylation stimulated by collagen I alone

• A factor that complicates the use of human liver

  2021-04-15

  

  A factor that complicates the use of human liver Sulfo-NHS-SS-Biotin is one of variability, which arises in part because many of the human liver samples available for research show various stages of a variety of disease states (steatosis (fatty liver), cirrhosis, carcinogenesis in adjacent tissue),

• ap4 australia Inflammatory action of certain cytokines can i

  2021-04-14

  

  Inflammatory action of certain cytokines can influence cell proliferative routes (Deshmane et al., 2009). When mTOR is inhibited, for instance by the action of Rapa, TGF-β1, which has an anti-inflammatory action, is increased. The relationship between high levels of TGF-β1 and ap4 australia arrest

• br Experimental section br Results and discussion br Conclus

  2021-04-14

  

  Experimental section Results and discussion Conclusions In conclusion, we have presented an autocatalytic recycling amplification electrochemical biosensing platform for simple, rapid and ultrasensitive detection of MTase activity by combining methylation-sensitive restriction endonuclease

• While the mechanism of DHODH inhibition

  2021-04-14

  

  While the mechanism of DHODH inhibition-induced differentiation is not fully understood, this phenomenon may be caused by pyrimidine depletion. Pyrazofurin, an inhibitor of OMP decarboxylase, was able to induce differentiation and suggests pyrimidine depletion as a potential mechanism (Sykes et al.,

• Interest in DGKs increased as it became clear

  2021-04-14

  

  Interest in DGKs increased as it became clear that not only are they important for lipid homeostasis, they serve to modulate the relative levels of diacylglycerol (DAG) and phosphatidic VE-822 (PtdOH) that play critical roles in a variety of signaling pathways (Eichmann and Lass, 2015; Liu et al.,

• It has been reported that vernolic

  2021-04-14

  

  It has been reported that vernolic 175 accumulation in transgenic Arabidopsis seeds expressing a Δ12-epoxygenase often resulted in failure of germination and impaired growth and development (Singh et al., 2001). Similar phenomena were also reported for transgenic Arabidopsis seeds with accumulation

• br Experimental procedures br Introduction Protein kinases r

  2021-04-14

  

  Experimental procedures Introduction Protein kinases represent one of the largest enzyme Cy5 RNA mg in the human genome and act as signaling mediators in a variety of cellular processes (Manning et al., 2002). Because many diseases are associated with aberrant protein kinase activity, targete

• DDR distribution in healthy fibrotic and inflamed tissues

  2021-04-14

  

  DDR1 distribution in healthy, fibrotic and inflamed tissues Whereas we can easily mine publicly available databases to infer DDR1 expression profile in different tissues (as reported in Fig. 1), fine comprehension of DDR1 biology has been hampered by the absence of a commercially available specific

• br Introduction Cardiovascular disease continues

  2021-04-14

  

  Introduction Cardiovascular disease continues to be the leading cause of death in developed countries. Atherosclerosis, a chronic inflammatory cardiovascular disease, is characterized by the progressive buildup of oxidized low density lipoproteins in the arterial walls (Ross, 1999). In the develo

• Ligand independent constitutively active variants have also

  2021-04-14

  

  Ligand-independent, constitutively active variants have also been found in receptors with associated tyrosine kinases. In approximately 60% of patients harboring inflammatory hepatocellular adenomas (IHCAs), these adenomas have been caused by small in-frame deletions in the cytokine-binding domain o

• Regarding the effects of CRF

  2021-04-14

  

  Regarding the effects of CRF on anxiety, Sahuque et al. (2006) have demonstrated that this neuropeptide also enhances anxiety when injected into the bed nucleus of the stria terminalis (BNST), a lysophosphatidic acid structure that has also been related to defensive behavior (Casada and Dafny, 1991

• Methylated CpGs can recruit transcriptional

  2021-04-14

  

  Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing CAL-101 structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared to Mr (Fig. 3b). However,

• Notochord is a transient structure differentiating at

  2021-04-14

  

  Notochord is a transient structure differentiating at early stage during embryogenesis that is at the origin of vertebral bodies in all vertebrates. In zebrafish, it is composed of vacuolated Gliotoxin surrounded by a unique ECM structure improperly called notochordal BM. As in chicken and amphibia

15652 records 639/1044 page Previous Next First page 上5页 636637638639640 下5页 Last page