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The following are the supplementary related
2018-11-12

The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä
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br Acknowledgments This study was
2018-11-12

Acknowledgments This study was funded by a grant provided by the Royan Institute. We thank Mr. Ehsan Janzamin for his unlimited assistance in the Flow Cytometry Laboratory, Dr. Abass Piryaei and Leila Sattarian in the Histology Laboratory, Mr. Chehrazi for statistical analysis, and Miss Saloomeh
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br Materials and methods br
2018-11-12

Materials and methods Acknowledgments Introduction Estimations suggest that more than one billion cardiomyocytes will be required per patient for cardiac replacement therapies after myocardial infarction (Murry et al., 2006). Human embryonic stem PXD101 (hESC) present an attractive cell sou
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To test their potential to reprogram
2018-11-12

To test their potential to reprogram, WT- and KO-MEFs were transfected with standard 4F (Oct4, Sox2, Klf4, and c-Myc) lentiviral constructs. KO-MEFs (KO+4F) reprogrammed colonies developed 7–10 days earlier and more efficiently (15- to 40-fold) than WT-MEFs (WT+4F) in five independent experiments (T
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Chondrogenic differentiation in our model is affected by der
2018-11-12

Chondrogenic differentiation in our model is affected by deregulation of LMNA, especially in PG-MSCs, as revealed by a lowered COL2/COL1 ratio and lower expression of COL2 and AGG as shown by real-time RT-PCR. While our findings do not completely agree with the results of the study by Scaffidi and M
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br Acknowledgments br This work
2018-11-12

Acknowledgments This work was supported by grants from the Juvenile Diabetes Research Foundation, Stanford Medical School Child Health Research Institute funded by the Stanford NIH/NCRR CTSA award number UL1 RR025744 and by the Lucile Packard Foundation for Children\'s Health (to NW), Arthritis
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br Acknowledgments We thank Anke Leinhaas and
2018-11-12

Acknowledgments We thank Anke Leinhaas and Conny Thielen for excellent technical support. We thank the members of the histology laboratory of the Institute of Neuropathology, University of Bonn, for technical assistance with EB and teratoma staining and members of the Stem Cell Engineering Group
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AS1404 cost Interestingly the Mst iPSC also demonstrated a h
2018-11-12

Interestingly, the Mst1−/− iPSC also demonstrated a higher proliferation rate compared to WT iPSC indicating that the reprogrammed AS1404 cost retained the properties of the source cells in terms of proliferation rate. Analysis of the Hippo signalling pathway in these cells suggested a marked activ
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br Introduction Foundational cell fate reprogramming studies
2018-11-12

Introduction Foundational cell fate reprogramming studies revealed ectopic expression of pluripotency-associated transcription factors (TF) OCT4, SOX2, KLF4, and c-MYC (OSKM) or OCT4, SOX2, NANOG, LIN28 (OSNL) in human fibroblasts (hFibs) cultured in pluripotent supportive conditions was sufficie
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br Specification of the mammalian germ cell lineage is an
2018-11-09

Specification of the mammalian germ cell lineage is an inductive process In model organisms such as Drosophila, C.elegans, Xenopus and Danio (zebrafish), PGCs are created each generation through a process known as pre-formation. This is a process driven by RNAs and proteins inherited from the ooc
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Previous studies including one in normal human
2018-11-09

Previous studies, including one in normal human fibroblasts, have demonstrated that HR activity is virtually absent during G1 phase, increases sharply in S phase, and begins to decrease by G2/M, whereas NHEJ activity occurs throughout the melatonin receptor agonist (Mao et al., 2008; Saleh-Gohari a
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Pluripotent ESCs and induced pluripotent stem
2018-11-09

Pluripotent ESCs and induced pluripotent stem Flavopiridol hydrochloride (iPSCs) represent a potentially unlimited source of skeletal cells for therapeutic applications. Several studies have established defined culture conditions to direct differentiation of mouse/human ESCs and human iPSCs into ch
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br Acknowledgments The study has been conducted with the
2018-11-09

Acknowledgments The study has been conducted with the financial support of the Russian Foundation for Basic Research (Grant no. 15-01-07923). Introduction Studying the scattering processes of charged and neutral particles of various natures is one of the most important problems in adenosine r
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kras-pdeδ inhibitor The second hypothesis relates to infants
2018-11-09

The second kras-pdeδ inhibitor relates to infants’ iron stores at birth, which form infants’ primary source of iron for the first months of life. Iron status of mothers during pregnancy is a key determinant of infant iron stores at birth (Allen, 2000). In our ENSIN sample we find that infants (6–12
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br Materials and methods br Results
2018-11-09

Materials and methods Results and discussion Conclusions The centre composite design of response surface methodology was successfully used in optimising the reaction conditions for biodiesel production from waste vegetable oil in the presence of csf-1r heterogeneous catalyst prepared from e
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