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HBV DNA levels are associated with clinically
2019-05-04
HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo
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tropisetron Bacterial LPS stimulates monocytes and
2019-05-04
Bacterial LPS stimulates monocytes and tissue macrophages to release TNF-α and IL-1, which then stimulate secondary response cytokines, including IL-6. In addition to hematopoietic cells, IL-6 is synthesized by many different types of nonhematopoietic cells, including endothelium, lasting for an ext
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Currently we are unable to fully understand the
2019-05-04
Currently, we are unable to fully understand the Phos-tag and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the present
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Preamble The J wave syndromes
2019-05-04
Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology JQ1 over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1992 [1]. The
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Despite our best efforts the cause
2019-05-04
Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po
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br Current approaches to HIV
2019-05-04
Current approaches to HIV prevention typically target people who are identified as, or self-identify, with being at risk. In Africa, 74% of new HIV infections are among adolescent girls aged 15–19 years, and AIDS-related illnesses are the leading cause of death among adolescent girls and women of
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br Sebastian Vollmer and colleagues April conclude
2019-05-04
Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the fasudil in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called trickle-down approach of a gr
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The circadian variation of VF
2019-04-30
The circadian variation of VF shows a similar nocturnal pattern in patients with BS and ERS [32] (Fig. 2). This is in contrast to the circadian pattern of VTAs in patients with ischemic heart diseases [33]. In a Korean cohort of patients with ERS and BS who underwent implantable cardioverter defibri
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A systematic review of population
2019-04-30
A systematic review of 56 population-based studies of the incidence and early case fatality of stroke, published from 1970 to 2008, showed that, in ten low-income and middle-income countries, the age-adjusted incidence of stroke more than doubled, from 52 per 100 000 person-years in 1970–79 to 117 p
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En este sentido la idea de crisis alude ante
2019-04-30
En este sentido, la idea de crisis alude ante todo, dilution examples una noción de cambio, que puede ser abrupto y radical —como en la noción de cambio revolucionario, o en la teoría de la crisis del capitalismo como colapso; o puede referirse más bien a una modificación o trastocamiento paulatino,
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br Drug resistance In clinical
2019-04-30
Drug resistance In clinical practice, there is no cross–drug-resistance between As2O3 and RA or other antileukemic agents. This may be explained by the non-liposoluble nature of As2O3, its small molecular weight, and its distinctive modes of action [20]. In our observation, primary As2O3 resistan
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Preventive chemotherapy for schistosomiasis is rapidly scali
2019-04-30
Preventive chemotherapy for schistosomiasis is rapidly scaling up worldwide. The global coverage that was less than 10% in 2010 is now higher than 30%, however, the main limitation for the scaling up is the availability of donated drug. In school age children, the age group for which praziquantel is
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Brugada syndrome BS is a hereditary arrhythmogenic disease
2019-04-30
Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada
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br Materials and methods This
2019-04-30
Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate purchase fexofenadine hydrochloride of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with l
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Any abnormality causing a loss of
2019-04-30
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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