• Appendiceal diverticular diseases are typically classified i

  2018-11-12

  

  Appendiceal diverticular diseases are typically classified into 4 main subtypes. Type 1 is diverticulitis with a normal appendix; Type 2 is diverticulitis with appendicitis; Type 3 is a noninflamed diverticulum with appendicitis; and Type 4 is a noninflamed diverticulum with a normal appendix. Type

• br Conclusion br Introduction Pilocytic astrocytoma PCA

  2018-11-12

  

  Conclusion Introduction Pilocytic astrocytoma (PCA; WHO Grade 1) has a benign biologic behavior and carries one of the highest survival rates among all types of astrocytoma. However, it occasionally shows atypical behavior characterized by local recurrence or, rarely, by malignant transformati

• br Discussion Spontaneous rupture of an umbilical hernia in

  2018-11-12

  

  Discussion Spontaneous rupture of an umbilical hernia in children is extremely rare and occurs predominantly in cirrhotic patients. The first reported case of spontaneous rupture of an umbilical hernia from ascites was reported by Mixter in 1901. MacLean recorded spontaneous rupture in a 3-month-

• How can we ensure the safety of the remnant

  2018-11-12

  

  How can we ensure the safety of the remnant liver margin when the safety cannot be determined at the time of the surgical procedure? The application of a saline-linked dissecting device on the in situ margins after tumorectomy could induce a substantial heat-zone area ranging from 10 mm to 13 mm wit

• br Materials and methods br Results and

  2018-11-12

  

  Materials and methods Results and discussion Conclusion In summary, some members of the fecal bacteria utilized garlic fructans to grow resulting in a decrease in the pH of the cultures in vitro. Bifidobacteria were stimulated while Clostridia were inhibited by the garlic fructans. Essentia

• The following are the supplementary related

  2018-11-12

  

  The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä

• br Acknowledgments This study was

  2018-11-12

  

  Acknowledgments This study was funded by a grant provided by the Royan Institute. We thank Mr. Ehsan Janzamin for his unlimited assistance in the Flow Cytometry Laboratory, Dr. Abass Piryaei and Leila Sattarian in the Histology Laboratory, Mr. Chehrazi for statistical analysis, and Miss Saloomeh

• br Materials and methods br

  2018-11-12

  

  Materials and methods Acknowledgments Introduction Estimations suggest that more than one billion cardiomyocytes will be required per patient for cardiac replacement therapies after myocardial infarction (Murry et al., 2006). Human embryonic stem PXD101 (hESC) present an attractive cell sou

• To test their potential to reprogram

  2018-11-12

  

  To test their potential to reprogram, WT- and KO-MEFs were transfected with standard 4F (Oct4, Sox2, Klf4, and c-Myc) lentiviral constructs. KO-MEFs (KO+4F) reprogrammed colonies developed 7–10 days earlier and more efficiently (15- to 40-fold) than WT-MEFs (WT+4F) in five independent experiments (T

• Chondrogenic differentiation in our model is affected by der

  2018-11-12

  

  Chondrogenic differentiation in our model is affected by deregulation of LMNA, especially in PG-MSCs, as revealed by a lowered COL2/COL1 ratio and lower expression of COL2 and AGG as shown by real-time RT-PCR. While our findings do not completely agree with the results of the study by Scaffidi and M

• br Acknowledgments br This work

  2018-11-12

  

  Acknowledgments This work was supported by grants from the Juvenile Diabetes Research Foundation, Stanford Medical School Child Health Research Institute funded by the Stanford NIH/NCRR CTSA award number UL1 RR025744 and by the Lucile Packard Foundation for Children\'s Health (to NW), Arthritis

• br Acknowledgments We thank Anke Leinhaas and

  2018-11-12

  

  Acknowledgments We thank Anke Leinhaas and Conny Thielen for excellent technical support. We thank the members of the histology laboratory of the Institute of Neuropathology, University of Bonn, for technical assistance with EB and teratoma staining and members of the Stem Cell Engineering Group

• AS1404 cost Interestingly the Mst iPSC also demonstrated a h

  2018-11-12

  

  Interestingly, the Mst1−/− iPSC also demonstrated a higher proliferation rate compared to WT iPSC indicating that the reprogrammed AS1404 cost retained the properties of the source cells in terms of proliferation rate. Analysis of the Hippo signalling pathway in these cells suggested a marked activ

• br Introduction Foundational cell fate reprogramming studies

  2018-11-12

  

  Introduction Foundational cell fate reprogramming studies revealed ectopic expression of pluripotency-associated transcription factors (TF) OCT4, SOX2, KLF4, and c-MYC (OSKM) or OCT4, SOX2, NANOG, LIN28 (OSNL) in human fibroblasts (hFibs) cultured in pluripotent supportive conditions was sufficie

• br Specification of the mammalian germ cell lineage is an

  2018-11-09

  

  Specification of the mammalian germ cell lineage is an inductive process In model organisms such as Drosophila, C.elegans, Xenopus and Danio (zebrafish), PGCs are created each generation through a process known as pre-formation. This is a process driven by RNAs and proteins inherited from the ooc

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