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Given the inexistence of market value for
2018-11-13
Given the inexistence of market value for all firms in our database, we account for investment opportunity by two different types of proxies. Following the empirical literature, in terms of covariate, we control for variables that capture investment opportunity in sectorial and firms’ level. In sect
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Despite the success of targeted therapies many genomic alter
2018-11-13
Despite the success of targeted therapies, many genomic alterations are considered “undruggable”. One such example is the above-mentioned t(11,14)(q13, 32) translocation, which increases the expression of cyclin D1 (). Another example of such an undruggable target is CD22ΔE12, described in a researc
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Due to their buoyancy circulating
2018-11-13
Due to their buoyancy, circulating tumor purchase GKPIPNPLLGLDST (CTCs) are found in the white blood cell fraction. CTCs have been investigated as a non-radiographic tool to monitor disease progression. The presence of CTCs suggests increased metastatic potential, and they have been investigated as
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Disclosure br Pericardial disorders constitute a relatively
2018-11-13
Disclosure Pericardial disorders constitute a relatively common cause of heart disease accounting for 0.1–0.2% of all hospital admissions (). From a clinical point of view pericardial syndromes encompass acute pericarditis (including relapses in the setting of recurrent forms), chronic constricti
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dhfr inhibitor HLA D expressed by antigen presenting cells A
2018-11-13
HLA-D, expressed by antigen presenting cells (APCs), hosts in the peptide-binding groove the antigenic fragments to present to T cell receptor (TCR) on cognate T cells. The polymorphisms of HLA-D molecules can change the amino-acid side chains of the binding pockets, altering the TCR-peptide-HLA-D i
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br Discussion Clinically extraocular SC often appears as a p
2018-11-12
Discussion Clinically, extraocular SC often appears as a pink to red-yellow nodule, but can exhibit diverse clinical presentations and is commonly confused with other lesions, especially basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The tumor may appear on top of pre-existing derm
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The overall economic burden caused by
2018-11-12
The overall economic burden caused by HZ includes treatment cost including antiviral and analgesia, consultation fee, hospitalization cost, and indirect cost due to absenteeism from work. The overall costs were highest in the labor productive age group, due to increased significant indirect costs be
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Primary thyroid malignancies typically do not interfere with
2018-11-12
Primary thyroid malignancies typically do not interfere with thyroid function. As such, a clinical presentation with hyperthyroidism is rare, except when there is rapid growth of the tumor within the thyroid with concomitant tissue destruction. The proposed mechanism by Sekiguchi et al for thyrotoxi
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Experimental tests showed that the impulse
2018-11-12
Experimental tests showed that the impulse transfer increases strongly with increasing purchase (RS)-CPP moisture content [16]. In order to take into account this effect a correction factor was defined to modify the specific impulses calculated with the above presented formulae. The correction facto
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A valid solution of Eq is assumed to
2018-11-12
A valid solution of Eq. (13) is assumed to exist for a projectile pressure sufficient to satisfy Eq. (12) and so that is the largest of the three-root solution. The critical crack length is therefore a constant for each grade of prestress since in Eq. (13) is a fix function. In agreement with this a
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Thus aforementioned research questions induce the following
2018-11-12
Thus, aforementioned research questions induce the following objectives that the study targets to achieve: 2. Conceptual relevance of import order citco industrialisation The ISI policy initiative has been faced with various criticisms over the past decades. The policy initiative was (and still
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In our study we first obtained a panel of anti
2018-11-12
In our study, we first obtained a panel of anti-pre-S antibodies, including one antibody highly specific for pre-S1 domain, and one specific for pre-S2 domain. We also harvested an antibody that could efficiently recognize the LHBs, and evaluated it’s clinical application. Of our recruited 537 patie
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In Flanders long lasting massive brick
2018-11-12
In Flanders long-lasting massive brick constructions are characteristic, especially within the housing market. Such houses own concrete floors installed in situ with raw materials or with prefabricated elements. The walls outside and inside are mostly brickwork. Outside walls are layered: inside wal
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Looking for a second time at the
2018-11-12
Looking for a second time at the forewords of the organizers and the supporters of such big events as the Expositions Universelles, we see the contemporary Expos from a bit more of a distance. If economics, politics and the market are the main engines of the machine which implements the Expos, we ca
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Obtaining direct access to all
2018-11-12
Obtaining direct access to all three types of actual projects is difficult; therefore, we seek assistance from other researchers. Case 1 (Li, 2012) and 3 (Sun, 2006) have been analyzed in previous studies, and the details of energy data are sufficient for our analysis. For Case 2, we conducted field
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